Be sure that you must stay in diagonal, to avoid its beam and waves. Be careful while running away from this creature, because two of them can send you to your temple. If you are stopped, you must heal with health above 350.
They don't deal very high combos, but they are stronger and faster than normal dragons.
Mages should use Death Strike or Ice Strike. Druids could use Hailstorm Rod or Underworld Rod, while Sorcerers could use Wand of Voodoo. A mage can kill a wyrm alone in level 80, without Mana Shield and healing when necessary. Paladins can easily run these as they would a dragon, but beware of luring other wyrms on yourself. It is a good idea to cast Divine Caldera and stairhop places with 2 or more wyrms.
Wyrms' bodies disappear after a very short time. It is not a good idea to leave items in their bodies if you want them.
It's a good idea to use Strange Talisman since it reduces the Energy Damage by 10%. Lightning Set is aswell recommended, because it has no charges, and wyrms drop lots of gps.